In Vivo Time-Course Imaging of Tumor Angiogenesis in Colorectal Liver Metastases in the Same Living Mice Using Two-Photon Laser Scanning Microscopy

In vivo real-time visualization of the process of angiogenesis in secondary tumors in the same living animals presents a major challenge in metastasis research. We developed a technique for intravital imaging of colorectal liver metastasis development in live mice using two-photon laser scanning mic...

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Bibliographic Details
Main Authors: Koji Tanaka, Yuhki Morimoto, Yuji Toiyama, Kohei Matsushita, Mikio Kawamura, Yuhki Koike, Yoshinaga Okugawa, Yasuhiro Inoue, Keiichi Uchida, Toshimitsu Araki, Akira Mizoguchi, Masato Kusunoki
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2012/265487