COX2 expression is associated with proliferation and tumor extension in vestibular schwannoma but is not influenced by acetylsalicylic acid intake

COX2 expression is associated with proliferation and tumor extension in vestibular schwannoma but is not influenced by acetylsalicylic acid intake

Abstract Acetylsalicylic acid has been linked to a lower risk for different cancer types, presumably through its inhibitory effect on cyclooxygenase 2. This has also been investigated in vestibular schwannomas with promising results suggesting an antiproliferative effect and recently the intake has...

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Bibliographic Details
Main Authors: Felix Behling, Vanessa Ries, Marco Skardelly, Irina Gepfner-Tuma, Martin Schuhmann, Florian-Heinrich Ebner, Ghazaleh Tabatabai, Antje Bornemann, Jens Schittenhelm, Marcos Tatagiba
Format: Article
Language:English
Published: BMC 2019-07-01
Series:Acta Neuropathologica Communications
Subjects:
Cyclooxygenase 2
Acetylsalicylic acid
Aspirin
Vestibular schwannoma
Acoustic neuroma
Neurofibromatosis
Online Access:http://link.springer.com/article/10.1186/s40478-019-0760-0

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http://link.springer.com/article/10.1186/s40478-019-0760-0

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