Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue

Perilipin regulates the thermogenic actions of norepinephrine in brown adipose tissue

In response to cold, norepinephrine (NE)-induced triacylglycerol hydrolysis (lipolysis) in adipocytes of brown adipose tissue (BAT) provides fatty acid substrates to mitochondria for heat generation (adaptive thermogenesis). NE-induced lipolysis is mediated by protein kinase A (PKA)-dependent phosph...

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Bibliographic Details
Main Authors: Sandra C. Souza, Marcelo A. Christoffolete, Miriam O. Ribeiro, Hideaki Miyoshi, Katherine J. Strissel, Zlatina S. Stancheva, Nicole H. Rogers, Tara M. D'Eon, James W. Perfield, II, Hitomi Imachi, Martin S. Obin, Antonio C. Bianco, Andrew S. Greenberg
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Journal of Lipid Research
Subjects:
norepinephrine-induced thermal response
protein kinase A-stimulated lipolysis
brown adipocytes
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520425556

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http://www.sciencedirect.com/science/article/pii/S0022227520425556

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