Myotonic Dystrophy—A Progeroid Disease?

Myotonic Dystrophy—A Progeroid Disease?

Myotonic dystrophies (DM) are slowly progressing multisystemic disorders caused by repeat expansions in the DMPK or CNBP genes. The multisystemic involvement in DM patients often reflects the appearance of accelerated aging. This is partly due to visible features such as cataracts, muscle weakness,...

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Bibliographic Details
Main Authors: Peter Meinke, Stefan Hintze, Sarah Limmer, Benedikt Schoser
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Neurology
Subjects:
myotonic dystrophy
segmental progeroid disorder
nuclear envelope
premature aging
DNA repair
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2018.00601/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2018.00601/full

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