CXCL13-producing PD-1hiCXCR5− helper T cells in chronic inflammation
CXCL13-producing PD-1hiCXCR5−CD4+ T cells were discovered in synovial tissues of rheumatoid arthritis (RA). Further intensive analysis of RA samples led to the proposal of PD-1hiCXCR5−CD4+ T cells as a pathogenic CD4 subset, peripheral helper T (Tph) cells. Tph cells are upregulated also in the peri...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2020-10-01
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| Series: | Immunological Medicine |
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| Online Access: | http://dx.doi.org/10.1080/25785826.2020.1781998 |