Infection-dependent phenotypes in MHC-congenic mice are not due to MHC: can we trust congenic animals?

Infection-dependent phenotypes in MHC-congenic mice are not due to MHC: can we trust congenic animals?

<p>Abstract</p> <p>Background</p> <p>Congenic strains of mice are assumed to differ only at a single gene or region of the genome. These mice have great importance in evaluating the function of genes. However, their utility depends on the maintenance of this true congen...

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Bibliographic Details
Main Authors: Wilkinson Maureen, Richardson Kelly S, Nibley Megan, Ma Maggie S, Groesbeck Zack J, Gardner Kyle, Damjanovich Kristy, McClelland Erin E, Morrison Linda C, Bernhardt Paul, Potts Wayne K
Format: Article
Language:English
Published: BMC 2004-07-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/5/14

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http://www.biomedcentral.com/1471-2172/5/14

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