GB-2 inhibits ACE2 and TMPRSS2 expression: In vivo and in vitro studies

After the first case of Coronavirus disease 2019 (COVID-19) was reported in Wuhan, COVID-19 has rapidly spread to almost all parts of world. Angiotensin converting enzyme 2 (ACE2) receptor can bind to spike protein of SARS-CoV-2. Then, the spike protein of SARS-CoV-2 can be cleaved and activated by...

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Bibliographic Details
Main Authors: Ching-Yuan Wu, Yu-Shih Lin, Yao-Hsu Yang, Li-Hsin Shu, Yu-Ching Cheng, Hung Te Liu
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S075333222031009X