Temozolomide-Induced RNA Interactome Uncovers Novel LncRNA Regulatory Loops in Glioblastoma

Temozolomide-Induced RNA Interactome Uncovers Novel LncRNA Regulatory Loops in Glioblastoma

Resistance to chemotherapy by temozolomide (TMZ) is a major cause of glioblastoma (GBM) recurrence. So far, attempts to characterize factors that contribute to TMZ sensitivity have largely focused on protein-coding genes, and failed to provide effective therapeutic targets. Long noncoding RNAs (lncR...

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Bibliographic Details
Main Authors: Sabrina Fritah, Arnaud Muller, Wei Jiang, Ramkrishna Mitra, Mohamad Sarmini, Monika Dieterle, Anna Golebiewska, Tao Ye, Eric Van Dyck, Christel Herold-Mende, Zhongming Zhao, Francisco Azuaje, Simone P. Niclou
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
glioblastoma
temozolomide
lncRNA
regulatory circuit
chemoresistance
transcriptome
Online Access:https://www.mdpi.com/2072-6694/12/9/2583

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https://www.mdpi.com/2072-6694/12/9/2583

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