Evaluation of the interaction between polymyxin B and Pseudomonas aeruginosa biofilm and planktonic cells: reactive oxygen species induction and zeta potential

Abstract Background Although the most widely accepted mechanism of action for polymyxins is related to bacterial lysis via disruption, we hypothesized that this antimicrobial drug class could have other effects on Pseudomonas aeruginosa planktonic and sessile cells. Little is known regarding oxidati...

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Bibliographic Details
Main Authors: Marlucy Rodrigues Lima, Gabriella Freitas Ferreira, Wallace Ribeiro Nunes Neto, Joveliane de Melo Monteiro, Áquila Rodrigues Costa Santos, Priscila Batista Tavares, Ângelo Márcio Leite Denadai, Maria Rosa Quaresma Bomfim, Vera Lúcia dos Santos, Sirlei Garcia Marques, Andrea de Souza Monteiro
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Microbiology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12866-019-1485-8