Exhaustive Enumeration of Kinetic Model Topologies for the Analysis of Time-Resolved RNA Folding

Exhaustive Enumeration of Kinetic Model Topologies for the Analysis of Time-Resolved RNA Folding

Unlike protein folding, the process by which a large RNA molecule adopts a functionally active conformation remains poorly understood. Chemical mapping techniques, such as Hydroxyl Radical (·OH) footprinting report on local structural changes in an RNA as it folds with single nucleotide resolution....

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Bibliographic Details
Main Authors: Alain Laederach, Katrina Simmons, Joshua S. Martin
Format: Article
Language:English
Published: MDPI AG 2009-02-01
Series:Algorithms
Subjects:
RNA folding
kinetic modeling
Tetrahymena thermophila group I intron
distributed computing
·OH radical footprinting.
Online Access:http://www.mdpi.com/1999-4893/2/1/200/

Internet

http://www.mdpi.com/1999-4893/2/1/200/

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