Adolescent Nicotine Exposure Alters GABAA Receptor Signaling in the Ventral Tegmental Area and Increases Adult Ethanol Self-Administration

Summary: Adolescent smoking is associated with pathological drinking later in life, but the biological basis for this vulnerability is unknown. To examine how adolescent nicotine exposure influences subsequent ethanol intake, nicotine was administered during adolescence or adulthood, and responses t...

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Bibliographic Details
Main Authors: Alyse M. Thomas, Alexey Ostroumov, Blake A. Kimmey, Madison B. Taormina, William M. Holden, Kristen Kim, Tiffany Brown-Mangum, John A. Dani
Format: Article
Language:English
Published: Elsevier 2018-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718303723