Pharmacological inhibition of myostatin improves skeletal muscle mass and function in a mouse model of stroke

Pharmacological inhibition of myostatin improves skeletal muscle mass and function in a mouse model of stroke

Abstract In stroke patients, loss of skeletal muscle mass leads to prolonged weakness and less efficient rehabilitation. We previously showed that expression of myostatin, a master negative regulator of skeletal muscle mass, was strongly increased in skeletal muscle in a mouse model of stroke. We th...

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Bibliographic Details
Main Authors: Marine Maud Desgeorges, Xavier Devillard, Jérome Toutain, Josiane Castells, Didier Divoux, David Frédéric Arnould, Christopher Haqq, Myriam Bernaudin, Anne-Cécile Durieux, Omar Touzani, Damien Gilles Freyssenet
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-13912-0

Internet

https://doi.org/10.1038/s41598-017-13912-0

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