PET imaging of hepatocellular carcinoma with anti-1-amino-3-[18F]fluorocyclobutanecarboxylic acid in comparison with l-[S-methyl-11C]methionine

PET imaging of hepatocellular carcinoma with anti-1-amino-3-[18F]fluorocyclobutanecarboxylic acid in comparison with l-[S-methyl-11C]methionine

Abstract Purpose [11C]methionine ([11C]Met) was used for cancer imaging based on upregulated amino acid transport and protein synthesis in different tumor types. However, the short half-life of 11C decay limited further clinical development of [11C]Met. Synthetic amino acid analog anti-1-amino-3-[18...

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Bibliographic Details
Main Authors: Olga Sergeeva, Yifan Zhang, Jonathan D. Kenyon, Galen A. Miller-Atkins, Chunying Wu, Renuka Iyer, Sandra Sexton, Patrick Wojtylak, Amad Awadallah, Wei Xin, E. Ricky Chan, James K. O’Donnel, Zhenghong Lee
Format: Article
Language:English
Published: SpringerOpen 2019-05-01
Series:EJNMMI Research
Subjects:
Amino acid transporter
Hepatocellular carcinoma
Woodchuck model
PET imaging
Online Access:http://link.springer.com/article/10.1186/s13550-019-0519-4

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http://link.springer.com/article/10.1186/s13550-019-0519-4

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