LIN28B promotes neuroblastoma metastasis and regulates PDZ binding kinase

LIN28B promotes neuroblastoma metastasis and regulates PDZ binding kinase

Neuroblastoma is an aggressive pediatric malignancy of the neural crest with suboptimal cure rates and a striking predilection for widespread metastases, underscoring the need to identify novel therapeutic vulnerabilities. We recently identified the RNA binding protein LIN28B as a driver in high-ris...

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Bibliographic Details
Main Authors: Dongdong Chen, Julie Cox, Jayabhargav Annam, Melanie Weingart, Grace Essien, Komal S. Rathi, Jo Lynne Rokita, Priya Khurana, Selma M. Cuya, Kristopher R. Bosse, Adeiye Pilgrim, Daisy Li, Cara Shields, Oskar Laur, John M. Maris, Robert W. Schnepp
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Neuroblastoma
LIN28B
Let-7
PDZ binding kinase
Metastasis
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558620301135

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http://www.sciencedirect.com/science/article/pii/S1476558620301135

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