Simulations of Promising Indolizidine—<i>α</i>6-<i>β</i>2 Nicotinic Acetylcholine Receptor Complexes

Simulations of Promising Indolizidine—<i>α</i>6-<i>β</i>2 Nicotinic Acetylcholine Receptor Complexes

Smoking-cessation drugs bind many off-target nicotinic acetylcholine receptors (nAChRs) and cause severe side effects if they are based on nicotine. New drugs that bind only those receptors, such as <inline-formula><math display="inline"><semantics><mi>α</mi>&...

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Bibliographic Details
Main Authors: Francis A. Acquah, Matthew Paramel, Adama Kuta, Syed R. Hussaini, David R. Wallace, Blaine H. M. Mooers
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:International Journal of Molecular Sciences
Subjects:
validation of virtual screening
hetero-oligomer membrane protein modeling
membrane protein-drug complexes
membrane protein dynamics simulations
smoking cessation
lung cancer
Online Access:https://www.mdpi.com/1422-0067/22/15/7934

Internet

https://www.mdpi.com/1422-0067/22/15/7934

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