Proteome Profiling of Exosomes Purified from a Small Amount of Human Serum: The Problem of Co-Purified Serum Components

Untargeted proteomics analysis of extracellular vesicles (EVs) isolated from human serum or plasma remains a technical challenge due to the contamination of these vesicles with lipoproteins and other abundant serum components. Here we aimed to test a simple method of EV isolation from a small amount...

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Bibliographic Details
Main Authors: Mateusz Smolarz, Monika Pietrowska, Natalia Matysiak, Łukasz Mielańczyk, Piotr Widłak
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Proteomes
Subjects:
Online Access:https://www.mdpi.com/2227-7382/7/2/18