Meta-analyses of KIF6 Trp719Arg in coronary heart disease and statin therapeutic effect.

The goal of our study is to assess the contribution of KIF6 Trp719Arg to both the risk of CHD and the efficacy of statin therapy in CHD patients.Meta-analysis of 8 prospective studies among 77,400 Caucasians provides evidence that 719Arg increases the risk of CHD (P<0.001, HR = 1.27, 95% CI = 1.1...

Full description

Bibliographic Details
Main Authors: Ping Peng, Jiangfang Lian, R Stephanie Huang, Limin Xu, Yi Huang, Yanna Ba, Xi Yang, Xiaoyan Huang, Changzhen Dong, Lina Zhang, Meng Ye, Jianqing Zhou, Shiwei Duan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3517591?pdf=render