Aurora kinase inhibitors synergize with paclitaxel to induce apoptosis in ovarian cancer cells

<p>Abstract</p> <p>Background</p> <p>A large percentage of patients with recurrent ovarian cancer develop resistance to the taxane class of chemotherapeutics. While mechanisms of resistance are being discovered, novel treatment options and a better understanding of dise...

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Bibliographic Details
Main Authors: McDonald John F, Logani Sanjay, Osunkoya Adeboye O, Laycock Noelani, Scharer Christopher D, Benigno Benedict B, Moreno Carlos S
Format: Article
Language:English
Published: BMC 2008-12-01
Series:Journal of Translational Medicine
Online Access:http://www.translational-medicine.com/content/6/1/79