Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study

Molecular features of untreated breast cancer and initial metastatic event inform clinical decision-making and predict outcome: long-term results of ESOPE, a single-arm prospective multicenter study

Abstract Background Prognosis evaluation of advanced breast cancer and therapeutic strategy are mostly based on clinical features of advanced disease and molecular profiling of the primary tumor. Very few studies have evaluated the impact of metastatic subtyping during the initial metastatic event i...

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Bibliographic Details
Main Authors: Céline Callens, Keltouma Driouch, Anaïs Boulai, Zakia Tariq, Aurélie Comte, Frédérique Berger, Lisa Belin, Ivan Bièche, Vincent Servois, Patricia Legoix, Virginie Bernard, Sylvain Baulande, Walid Chemlali, François-Clément Bidard, Virginie Fourchotte, Anne Vincent- Salomon, Etienne Brain, Rosette Lidereau, Thomas Bachelot, Mahasti Saghatchian, Mario Campone, Sylvie Giacchetti, Brigitte Sigal Zafrani, Paul Cottu
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Genome Medicine
Subjects:
Breast cancer
Metastasis
Next generation sequencing
Targetable genes
Prognosis
de novo metastases
Online Access:https://doi.org/10.1186/s13073-021-00862-6

Internet

https://doi.org/10.1186/s13073-021-00862-6

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