The NLRP3 Inflammasome and Its Role in T1DM

The NLRP3 Inflammasome and Its Role in T1DM

The NLRP3 (nucleotide-binding and oligomerization domain-like receptor family pyrin domain-containing 3) inflammasome is a protein complex expressed in cells. It detects danger signals and induces the production of active caspase-1 and the maturation and release of IL (interleukin)-33, IL-18, IL-1β...

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Bibliographic Details
Main Authors: Xiaoxiao Sun, Haipeng Pang, Jiaqi Li, Shuoming Luo, Gan Huang, Xia Li, Zhiguo Xie, Zhiguang Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
T1DM
NLRP3 inflammasome
IL-1β
innate immunity
autoimmune disorder
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01595/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01595/full

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