Targeting the HGF-cMET Axis in Hepatocellular Carcinoma

Under normal physiological conditions, the hepatocyte growth factor (HGF) and its receptor, the MET transmembrane tyrosine kinase (cMET), are involved in embryogenesis, morphogenesis, and wound healing. The HGF-cMET axis promotes cell survival, proliferation, migration, and invasion via modulation o...

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Bibliographic Details
Main Authors: Neeta K. Venepalli, Laura Goff
Format: Article
Language:English
Published: Hindawi Limited 2013-01-01
Series:International Journal of Hepatology
Online Access:http://dx.doi.org/10.1155/2013/341636