Effect of withholding early parenteral nutrition in PICU on ketogenesis as potential mediator of its outcome benefit

Effect of withholding early parenteral nutrition in PICU on ketogenesis as potential mediator of its outcome benefit

Abstract Background In critically ill children, omitting early use of parenteral nutrition (late-PN versus early-PN) reduced infections, accelerated weaning from mechanical ventilation, and shortened PICU stay. We hypothesized that fasting-induced ketogenesis mediates these benefits. Methods In a se...

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Bibliographic Details
Main Authors: Astrid De Bruyn, Jan Gunst, Chloë Goossens, Sarah Vander Perre, Gonzalo G. Guerra, Sascha Verbruggen, Koen Joosten, Lies Langouche, Greet Van den Berghe
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Critical Care
Subjects:
Parenteral nutrition
Intensive care
Ketogenesis
Ketone body
Recovery
Online Access:http://link.springer.com/article/10.1186/s13054-020-03256-z

Internet

http://link.springer.com/article/10.1186/s13054-020-03256-z

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