Intra-lineage Plasticity and Functional Reprogramming Maintain Natural Killer Cell Repertoire Diversity

Summary: Natural killer (NK) cell repertoires are made up of phenotypically distinct subsets with different functional properties. The molecular programs involved in maintaining NK cell repertoire diversity under homeostatic conditions remain elusive. Here, we show that subset-specific NK cell proli...

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Bibliographic Details
Main Authors: Aline Pfefferle, Benedikt Jacobs, Herman Netskar, Eivind Heggernes Ask, Susanne Lorenz, Trevor Clancy, Jodie P. Goodridge, Ebba Sohlberg, Karl-Johan Malmberg
Format: Article
Language:English
Published: Elsevier 2019-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719313725