A Novel Aurora Kinase Inhibitor Attenuates Leukemic Cell Proliferation Induced by Mesenchymal Stem Cells

A Novel Aurora Kinase Inhibitor Attenuates Leukemic Cell Proliferation Induced by Mesenchymal Stem Cells

Acute myeloid leukemia (AML) mesenchymal stem cells (MSCs) play an essential role in protecting leukemic cells from chemotherapeutic agents through activating a wide range of adhesion molecules and cytokines. Thus, more attention should be paid to attenuate the protection of leukemic cells by MSCs....

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Bibliographic Details
Main Authors: Jun-Dan Wang, Wei Zhang, Jing-Wen Zhang, Ling Zhang, Le-Xun Wang, Hong-Sheng Zhou, Liang Long, Gui Lu, Quentin Liu, Zi-Jie Long
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Oncolytics
Subjects:
Aurora kinase inhibitor
AML
leukemic microenvironment
cell proliferation
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520301182

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http://www.sciencedirect.com/science/article/pii/S2372770520301182

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