Administration of alpha klotho reduces liver and adipose lipid accumulation in obese mice

α-Klotho, a known anti-aging protein, exerts diverse physiological effects including: maintenance of phosphate and calcium homeostasis, modulation of cell proliferation, and enhanced buffering of reactive oxygen species. However, the role of α-Klotho in the regulation of energy metabolism is complex...

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Bibliographic Details
Main Authors: Zhijian Rao, Taylor Landry, Peixin Li, Wyatt Bunner, Brenton Thomas Laing, Yuan Yuan, Hu Huang
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844019303445