Intracellular delivery of nanoparticles and DNAs by IR9 cell-penetrating peptides.

Cell-penetrating peptides (CPPs) comprised of basic amino residues are able to cross cytoplasmic membranes and are able to deliver biologically active molecules inside cells. However, CPP/cargo entrapment in endosome limits biomedical utility as cargoes are destroyed in the acidic environment. In th...

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Bibliographic Details
Main Authors: Betty R Liu, Ji-Sing Liou, Yue-Wern Huang, Robert S Aronstam, Han-Jung Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3665793?pdf=render