Differences in intrinsic aerobic capacity alters sensitivity to ischemia-reperfusion injury but not cardioprotective capacity by ischemic preconditioning in rats.

<h4>Introduction</h4>Aerobic capacity is a strong predictor of cardiovascular mortality. Whether aerobic capacity influences myocardial ischemia and reperfusion (IR) injury is unknown.<h4>Purpose</h4>To investigate the impact of intrinsic differences in aerobic capacity and t...

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Main Authors: Marie Vognstoft Hjortbak, Thomas Skjærlund Grønnebæk, Nichlas Riise Jespersen, Thomas Ravn Lassen, Jacob Marthinsen Seefeldt, Pernille Tilma Tonnesen, Rebekka Vibjerg Jensen, Lauren Gerard Koch, Steven L Britton, Michael Pedersen, Niels Jessen, Hans Erik Bøtker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0240866