The pro-inflammatory signalling regulator Stat4 promotes vasculogenesis of great vessels derived from endothelial precursors

Stat4 is a transcription factor known to regulate pro-inflammatory signalling. Here, Menget al. show that Stat4 is not only regulating inflammation but it is also crucial for great vessels development and endothelial precursor proliferation in zebrafish, by inhibiting the expression of hdac3and coun...

Full description

Bibliographic Details
Main Authors: Zhao-Zheng Meng, Wei Liu, Yu Xia, Hui-Min Yin, Chi-Yuan Zhang, Dan Su, Li-Feng Yan, Ai-Hua Gu, Yong Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2017-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14640