Platelet desialylation is a novel mechanism and a therapeutic target in thrombocytopenia during sepsis: an open-label, multicenter, randomized controlled trial
Abstract Background Studies in murine models suggested that platelet desialylation was an important mechanism of thrombocytopenia during sepsis. Methods First, we performed a prospective, multicenter, observational study that enrolled septic patients with or without thrombocytopenia to determine the...
Main Authors: | , , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2017-05-01
|
Series: | Journal of Hematology & Oncology |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13045-017-0476-1 |