PNPLA3 p.I148M and TM6SF2 p.E167K variants do not predispose to liver injury in cholestatic liver diseases: A prospective analysis of 178 patients with PSC.

PNPLA3 p.I148M and TM6SF2 p.E167K variants do not predispose to liver injury in cholestatic liver diseases: A prospective analysis of 178 patients with PSC.

BACKGROUND:The adiponutrin (PNPLA3) p.I148M and transmembrane 6 superfamily member 2 (TM6SF2) p.E167K variants represent major genetic risk factors for progressive liver injury in nonalcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD) and chronic viral hepatitis. The aim of this stu...

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Bibliographic Details
Main Authors: Beata Kruk, Roman Liebe, Małgorzata Milkiewicz, Ewa Wunsch, Joanna Raszeja-Wyszomirska, Frank Lammert, Piotr Milkiewicz, Marcin Krawczyk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6117000?pdf=render

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http://europepmc.org/articles/PMC6117000?pdf=render

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