NormExpression: An R Package to Normalize Gene Expression Data Using Evaluated Methods

NormExpression: An R Package to Normalize Gene Expression Data Using Evaluated Methods

Data normalization is a crucial step in the gene expression analysis as it ensures the validity of its downstream analyses. Although many metrics have been designed to evaluate the existing normalization methods, different metrics or different datasets by the same metric yield inconsistent results,...

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Bibliographic Details
Main Authors: Zhenfeng Wu, Weixiang Liu, Xiufeng Jin, Haishuo Ji, Hua Wang, Gustavo Glusman, Max Robinson, Lin Liu, Jishou Ruan, Shan Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Genetics
Subjects:
gene expression
normalization
evaluation
R package
scRNA-seq
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00400/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2019.00400/full

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