Determination of optimized oxygen partial pressure to maximize the liver regenerative potential of the secretome obtained from adipose-derived stem cells

Determination of optimized oxygen partial pressure to maximize the liver regenerative potential of the secretome obtained from adipose-derived stem cells

Abstract Background A hypoxic-preconditioned secretome from stem cells reportedly promotes the functional and regenerative capacity of the liver more effectively than a control secretome. However, the optimum oxygen partial pressure (pO2) in the cell culture system that maximizes the therapeutic pot...

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Bibliographic Details
Main Authors: Sang Chul Lee, Kee-Hwan Kim, Ok-Hee Kim, Sang Kuon Lee, Ha-Eun Hong, Seong Su Won, Sang-Jin Jeon, Byung Jo Choi, Wonjun Jeong, Say-June Kim
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Stem Cell Research & Therapy
Subjects:
Adipose tissue-derived stem cells
Hypoxia
Liver regeneration
Sirtuin-1 (SIRT1)
Secretome
Online Access:http://link.springer.com/article/10.1186/s13287-017-0635-x

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http://link.springer.com/article/10.1186/s13287-017-0635-x

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