Circulating Pro-Vascular Progenitor Cell Depletion During Type 2 Diabetes

Summary: Detection of vascular regenerative cell exhaustion is required to combat ischemic complications during type 2 diabetes mellitus (T2D). We used high aldehyde dehydrogenase (ALDH) activity and surface marker co-expression to develop a high-throughput flow cytometry–based assay to quantify cir...

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Bibliographic Details
Main Authors: Daniella C. Terenzi, BHSc, Mohammed Al-Omran, MD, MSc, Adrian Quan, MPhil, Hwee Teoh, PhD, Subodh Verma, MD, PhD, David A. Hess, PhD
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:JACC: Basic to Translational Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X18302742