The chromatin Remodeler CHD8 is required for activation of progesterone receptor-dependent enhancers.
While the importance of gene enhancers in transcriptional regulation is well established, the mechanisms and the protein factors that determine enhancers activity have only recently begun to be unravelled. Recent studies have shown that progesterone receptor (PR) binds regions that display typical f...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-04-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4403880?pdf=render |