Andrographolide Alleviates Acute Brain Injury in a Rat Model of Traumatic Brain Injury: Possible Involvement of Inflammatory Signaling

Andrographolide Alleviates Acute Brain Injury in a Rat Model of Traumatic Brain Injury: Possible Involvement of Inflammatory Signaling

Neuroinflammation plays an important role in secondary injury after traumatic brain injury (TBI). Andrographolide (Andro), a diterpenoid lactone isolated from Andrographis paniculata, has been demonstrated to exhibit anti-inflammatory activity in neurodegenerative disorders. This study therefore aim...

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Bibliographic Details
Main Authors: Li Tao, Li Zhang, Rong Gao, Feng Jiang, Jianbo Cao, Huixiang Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Neuroscience
Subjects:
andrographolide
inflammation
apoptosis
traumatic brain injury
neuroprotection
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00657/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.00657/full

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