CombiFlow: Flow cytometry-based identification and characterization of genetically and functionally distinct AML subclones

Summary: Many cancers, including leukemias, are dynamic oligoclonal diseases. Tools to identify and prospectively isolate genetically distinct clones for functional studies are needed. We describe our CombiFlow protocol, which is a combinatorial flow cytometry-based approach to identify and isolate...

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Bibliographic Details
Main Authors: Roos Houtsma, Shanna M. Hogeling, Jan Jacob Schuringa
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166721005700