Selenoprotein T Protects Endothelial Cells against Lipopolysaccharide-Induced Activation and Apoptosis

Selenoprotein T Protects Endothelial Cells against Lipopolysaccharide-Induced Activation and Apoptosis

Sepsis is an exaggerated immune response upon infection with lipopolysaccharide (LPS) as the main causative agent. LPS-induced activation and apoptosis of endothelial cells (EC) can lead to organ dysfunction and finally organ failure. We previously demonstrated that the first twenty amino acids of t...

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Bibliographic Details
Main Authors: Dennis Merk, Johannes Ptok, Philipp Jakobs, Florian von Ameln, Jan Greulich, Pia Kluge, Kathrin Semperowitsch, Olaf Eckermann, Heiner Schaal, Niloofar Ale-Agha, Joachim Altschmied, Judith Haendeler
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Antioxidants
Subjects:
APEX1(1-20)
Selenoprotein T
lipopolysaccharide
endothelial cell activation
apoptosis
Online Access:https://www.mdpi.com/2076-3921/10/9/1427

Internet

https://www.mdpi.com/2076-3921/10/9/1427

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