The synthetic bacterial lipopeptide Pam3CSK4 modulates respiratory syncytial virus infection independent of TLR activation.

Respiratory syncytial virus (RSV) is an important cause of acute respiratory disease in infants, immunocompromised subjects and the elderly. However, it is unclear why most primary RSV infections are associated with relatively mild symptoms, whereas some result in severe lower respiratory tract infe...

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Bibliographic Details
Main Authors: D Tien Nguyen, Lot de Witte, Martin Ludlow, Selma Yüksel, Karl-Heinz Wiesmüller, Teunis B H Geijtenbeek, Albert D M E Osterhaus, Rik L de Swart
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2924323?pdf=render