Lithium reverses increased rates of cerebral protein synthesis in a mouse model of fragile X syndrome

Lithium reverses increased rates of cerebral protein synthesis in a mouse model of fragile X syndrome

Individuals with fragile X syndrome (FXS), an inherited form of cognitive disability, have a wide range of symptoms including hyperactivity, autistic behavior, seizures and learning deficits. FXS is caused by silencing of FMR1 and the consequent absence of fragile X mental retardation protein (FMRP)...

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Bibliographic Details
Main Authors: Zhong-Hua Liu, Tianjian Huang, Carolyn Beebe Smith
Format: Article
Language:English
Published: Elsevier 2012-03-01
Series:Neurobiology of Disease
Subjects:
Protein synthesis
Fragile X syndrome
Lithium
Fmr1
Mouse
Brain
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996111004128

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http://www.sciencedirect.com/science/article/pii/S0969996111004128

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