Assessment of the efficacy of repeated instillations of mitomycin C mixed with a thermosensitive hydrogel in an orthotopic rat bladder cancer model

Background: We investigated a thermoreversible hydrogel that is highly viscous at body temperature, while fluid-like at a low temperature, thus aiming for a slow and prolonged intravesical drug release. Our study purposed to assess antitumor efficacy of mitomycin C (MMC) mixed with hydrogel in an or...

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Bibliographic Details
Main Authors: F. Johannes P. van Valenberg, Dalit Strauss-Ayali, Yael Agmon-Gerstein, Astar Friedman, Harm C. Arentsen, H. Ewout Schaafsma, J. Alfred Witjes, Egbert Oosterwijk
Format: Article
Language:English
Published: SAGE Publishing 2018-07-01
Series:Therapeutic Advances in Urology
Online Access:https://doi.org/10.1177/1756287218762064