A new model for the population pharmacokinetics of didanosine in healthy subjects

Didanosine (ddI) is a component of highly active antiretroviral therapy drug combinations, used especially in resource-limited settings and in zidovudine-resistant patients. The population pharmacokinetics of ddI was evaluated in 48 healthy volunteers enrolled in two bioequivalence studies. These da...

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Bibliographic Details
Main Authors: L.S. Velasque, R.C.E. Estrela, G. Suarez-Kurtz, C.J. Struchiner
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2007-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2007000100013