Cholinesterase inhibitory activity of tinosporide and 8-hydroxytinosporide isolated from Tinospora cordifolia: In vitro and in silico studies targeting management of Alzheimer’s disease

Cholinesterase inhibitory activity of tinosporide and 8-hydroxytinosporide isolated from Tinospora cordifolia: In vitro and in silico studies targeting management of Alzheimer’s disease

Tinosporide and 8-hydroxytinosporide isolated from Tinospora cordifolia were evaluated for acetylcholinesterase (AChE) and butylcholinesterase (BuChE) inhibitory activities. The structure of the compound was confirmed by spectroscopic analysis, whereas cholinesterase inhibition was investigated by E...

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Bibliographic Details
Main Authors: Mohiminul Adib, Rashedul Islam, Monira Ahsan, Arifur Rahman, Mahmud Hossain, Md Mustafizur Rahman, Sultan M. Alshehri, Mohsin Kazi, Md Abdul Mazid
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Saudi Journal of Biological Sciences
Subjects:
Tinosporide
Acetylcholinesterase
Butyrylcholinesterse
ADMET analysis
Molecular docking
Online Access:http://www.sciencedirect.com/science/article/pii/S1319562X21002436

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http://www.sciencedirect.com/science/article/pii/S1319562X21002436

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