Quantification of HTLV-1 clonality and TCR diversity.

Estimation of immunological and microbiological diversity is vital to our understanding of infection and the immune response. For instance, what is the diversity of the T cell repertoire? These questions are partially addressed by high-throughput sequencing techniques that enable identification of i...

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Bibliographic Details
Main Authors: Daniel J Laydon, Anat Melamed, Aaron Sim, Nicolas A Gillet, Kathleen Sim, Sam Darko, J Simon Kroll, Daniel C Douek, David A Price, Charles R M Bangham, Becca Asquith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4063693?pdf=render