Interactions among ryanodine receptor isotypes contribute to muscle fiber type development and function

Interactions among ryanodine receptor isotypes contribute to muscle fiber type development and function

Mutations affecting ryanodine receptor (RyR) calcium release channels commonly underlie congenital myopathies. Although these channels are known principally for their essential roles in muscle contractility, mutations in the human RYR1 gene result in a broad spectrum of phenotypes, including muscle...

Full description

Bibliographic Details
Main Authors: Alexis A. Chagovetz, Dana Klatt Shaw, Erin Ritchie, Kazuyuki Hoshijima, David J. Grunwald, Annemieke Aartsma-Rus, James Dowling, Maaike van Putten
Format: Article
Language:English
Published: The Company of Biologists 2020-02-01
Series:Disease Models & Mechanisms
Subjects:
ryanodine receptors
congenital myopathy
zebrafish disease model
muscle development
muscle function
Online Access:http://dmm.biologists.org/content/13/2/dmm038844

Internet

http://dmm.biologists.org/content/13/2/dmm038844

Similar Items