Apolipoprotein L1 risk variants associate with prevalent atherosclerotic disease in African American systemic lupus erythematosus patients.

Atherosclerosis is exaggerated in African American (AA) systemic lupus erythematosus (SLE) patients, with doubled cardiovascular disease (CVD) risk compared to White patients. The extent to which common Apolipoprotein L1 (APOL1) risk alleles (RA) contribute to this trend is unknown. This retrospecti...

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Bibliographic Details
Main Authors: Ashira Blazer, Binhuan Wang, Danny Simpson, Tomas Kirchhoff, Sean Heffron, Robert M Clancy, Adriana Heguy, Karina Ray, Matija Snuderl, Jill P Buyon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5574561?pdf=render