In vivo CART cell imaging: Paving the way for success in CART cell therapy

Chimeric antigen receptor T (CART) cells are a promising immunotherapy that has induced dramatic anti-tumor responses in certain B cell malignancies. However, CART cell expansion and trafficking are often insufficient to yield long-term remissions, and serious toxicities can arise after CART cell ad...

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Bibliographic Details
Main Authors: Reona Sakemura, Ismail Can, Elizabeth L. Siegler, Saad S. Kenderian
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Oncolytics
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770521000358