Transporter-centric view of urate metabolism: From genome-wide association study to pathophysiology

While urate is an important anti-oxidant molecule in the body, high plasma levels of urate cause morbidity including urate crystal deposition in joints (gout) and stone formation in the urinary tract. Because urate is an end product of purine metabolism, it must be excreted from the body via the kid...

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Bibliographic Details
Main Author: Hiroyuki Sakurai
Format: Article
Language:English
Published: Japanese Society of Physical Fitness and Sports Medicine 2012-10-01
Series:Journal of Physical Fitness and Sports Medicine
Subjects:
Online Access:https://www.jstage.jst.go.jp/article/jpfsm/1/3/1_413/_pdf/-char/en