Biocatalytic Approach to Chiral β-Nitroalcohols by Enantioselective Alcohol Dehydrogenase-Mediated Reduction of α-Nitroketones

Chiral β-nitroalcohols are important building blocks in organic chemistry. The synthetic approach that is based on the enzyme-mediated reduction of α-nitroketones has been scarcely considered. In this work, the use of commercial alcohol dehydrogenases (ADHs) for the reduction of a...

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Bibliographic Details
Main Authors: Francesca Tentori, Elisabetta Brenna, Danilo Colombo, Michele Crotti, Francesco G. Gatti, Maria Chiara Ghezzi, Giuseppe Pedrocchi-Fantoni
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Catalysts
Subjects:
Online Access:http://www.mdpi.com/2073-4344/8/8/308