Development and validation of a real-time PCR for detection of pathogenic leptospira species in clinical materials.

Available serological diagnostics do not allow the confirmation of clinically suspected leptospirosis at the early acute phase of illness. Several conventional and real-time PCRs for the early diagnosis of leptospirosis have been described but these have been incompletely evaluated. We developed a S...

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Bibliographic Details
Main Authors: Ahmed Ahmed, Mirjam F M Engelberts, Kimberly R Boer, Niyaz Ahmed, Rudy A Hartskeerl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-09-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2740861?pdf=render