Generation of a FOXH1 homozygous knockout human embryonic stem cell line by CRISPR/Cas9 system

Human FOXH1 (Forkhead Box H1) gene encodes a human homolog of Xenopus forkhead activing signal transducer-1 and has been shown to play an important role in mesendoderm formation in X. tropicalis and mice. However, little is known about the function of FOXH1 in human development. Here we generated a...

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Bibliographic Details
Main Authors: Tian Zhang, Wanlan Huang, Xingkui Xue
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506120304220